Neurocognitive, Executive, and Behavioral Impairment in Sleep/Wake Disorders Mechanisms, Interindividual Differences, and Ongoing Management - Monograph
- Credit Type
- CME
- Credit Amount
- 1
- Release Date
- 12/17/2009
- Expiration Date
- 12/16/2010
- Activity Type
- Monograph
This monograph is based on a 2-hour symposium entitled Sleep/Wake Disorders: Long-term Neurocognitive, Executive, and Behavioral Consequences and Clinical Controversies, which took place on June 9, 2009 in Seattle, Washington.

Jointly sponsored by Albert Einstein College of Medicine, Montefiore Medical Center, and Asante Communications

This activity is supported by an educational grant from Cephalon, Inc.
Release Date: 12/17/2009
Expiration Date: 12/16/2010
Faculty
Michael J. Thorpy, MD / Course Director
Director
Sleep-Wake Disorders Center
Montefiore Medical Center
Professor of Neurology
Albert Einstein College of Medicine of Yeshiva University
Bronx, New York
Richard D. Simon Jr, MD
Clinical Assistant Professor of Medicine
University of Washington School of Medicine
Medical Director
Kathryn Severyns Dement Sleep Disorders Center
Providence St. Mary Medical Center
Walla Walla, Washington
Hans P.A. Van Dongen, PhD
Research Professor
Assistant Director
Sleep and Performance Research Center
Washington State University
Spokane, Washington
Matthew P. Walker, PhD
Director
Sleep and Neuroimaging Laboratory
Assistant Professor of Psychology and Neuroscience
Department of Psychology
Helen Wills Neuroscience Institute
University of California, Berkeley
Berkeley, California
Activity Goal
This monograph highlights scientific and clinical data emphasizing the relationship between sleep/wake disorders and the associated neurocognitive, neurophysiologic, and executive consequences.
Intended Audience
This activity is intended for sleep specialists and other healthcare providers interested in sleep/wake medicine.
There are no prerequisites for this educational activity.
Statement of Need
Developed for community-based sleep clinicians and designed to provide a scientific rationale for individualized assessment and treatment of patients with sleep/wake disorders, this program presents the neurobiological basis and potentially irreversible consequences of untreated disturbances in sleep/wake consolidation.
Learner’s Gap
Sleep/wake research continues to produce impressive and clinically relevant results. Recent advances in brain imaging, molecular neurobiology, and cognitive analysis reinforce the urgent rationale for diagnosis and treatment of patients with impaired sleep. Sleep/Wake disorders are heterogeneous, though all have profound effects on patient function. The disorders are prevalent, underrecognized, and undertreated. Inadequate treatment is associated with morbidity and mortality, an association gaining increased attention among clinical researchers. Healthcare-associated costs are prohibitively burdensome, estimated at nearly 100 billion dollars annually. Data from numerous epidemiological and randomized, controlled studies clearly demonstrate that patients with disrupted sleep/wake patterns have impaired function and experience excessive sleepiness, a debilitating symptom with far-reaching consequences. Sleep clinicians need to improve their understanding of the morbidity associated with sleep/wake disorders, to communicate the issues to their colleagues and patients, and to tailor therapies accordingly.
Learning Objectives
At the completion of this initiative, the participants should be better prepared to:
- Discuss the morbidity associated with sleep/wake disorders across neurocognitive, neurophysiologic, and executive domains.
- Explain the neurophysiologic basis of the potentially irreversible neurocognitive, memory, and executive deficits in patients with obstructive sleep apnea and other sleep/wake disorders, and their implications for diagnosis and treatment.
- Evaluate potential neuropsychologic and executive deficits in patients with obstructive sleep apnea, shift work disorder, narcolepsy, insufficient sleep syndrome, and other sleep/wake disorders.
- Monitor progress during treatment of patients with sleep/wake disorders, emphasizing neurocognitive and neurobehavioral function as outcome measures in development of clinical treatment plans.
- Employ nonpharmacologic and pharmacologic treatment modalities to improve sleep/wake consolidation and function in patients with sleep/wake disorders.
Accreditation Statement
This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Albert Einstein College of Medicine and Montefiore Medical Center, and Asante Communications. Albert Einstein College of Medicine is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation
Albert Einstein College of Medicine designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Conflict of Interest Statement
The Conflict of Interest Disclosure Policy of Albert Einstein College of Medicine requires that faculty participating in any CME activity disclose to
the audience any relationship(s) with a pharmaceutical, product, or device
company. Any presenter whose disclosed relationships
prove to create a conflict of interest with regard to their contribution to the
activity will not be permitted to present.
Albert Einstein College of Medicine also requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or
investigational use of any commercial product or device not yet approved for
use in the United States.
Faculty participating in this activity have reported the following disclosures:
Michael J. Thorpy, MD Cephalon, Inc.; Jazz Pharmaceuticals
(consultant, speakers bureau)
Richard D. Simon Jr, MD Ventus Medical (grant/research support);
The McMahon Group (honorarium)
Hans P.A. Van Dongen, PhD Dr Van Dongen has no conflicts of interest
to disclose
Matthew P. Walker, PhD Actelion Pharmaceuticals Ltd.,
sanofi-aventis (consultant)
One staff member at Albert Einstein College of Medicine has reported the
following disclosures:
Steven Jay Feld, or a member of his household, owns securities in Bioheart, Inc.; Chelsea Therapeutics, Inc.; and Pharmacopeia, Inc.
Chris Ontiveros, PhD, (senior scientific associate, Asante Communications, LLC) has no conflicts of interest with commercial interests related directly or indirectly to this educational activity.
Method of Participation
There are no fees for participating in and receiving credit for this activity. Participants must read the objectives and enduring material, and answer the multiple-choice posttest. Please complete the evaluation form, which enables you to comment on the quality of the instructional process, the perception of enhanced professional effectiveness and commercial bias, and express your views on future educational needs. A score of at least 70% is required to successfully complete this activity. Credit is available through December 16, 2010.
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Please read Albert Einstein College of Medicine's Privacy Policy. [See attached Privacy Policy]
If you have questions about this CME activity, please contact Albert Einstein College of Medicine at 718-920-6674 or cme@montefiore.org.
Copyright Information
Copyright © 2009 Albert Einstein College of Medicine and Montefiore Medical Center, and Asante Communications. All rights reserved. No part of this syllabus may be used or reproduced in any manner whatsoever without written permission, except in the case of brief quotations embodied in articles or reviews.
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