Obstructive Sleep Apnea and Circadian Rhythm Sleep Disorders - A Best Practices Report From the Cases & Commentary Workshop

Thomas Roth, PhD; Andrew D. Krystal, MD, MS; Andrew G Israel, MD; Michael J. Thorpy, MD
Credit Type
CME
Credit Amount
1
Release Date
02/16/2010
Expiration Date
02/15/2011
Activity Type
Monograph

Jointly sponsored by Albert Einstein College of Medicine, Montefiore Medical Center, and Asante Communications
 


This activity is supported by an educational grant from Cephalon, Inc.

Release Date: 2/16/10
Expiration Date
: 2/15/11

 

Activity Goal

This monograph highlights scientific and clinical data that promote best practices in the individualized assessment and management of patients with sleep/wake disorders.
 

Intended Audience

This activity is intended for sleep clinicians, primary care physicians, physician assistants, nurse practitioners, and other healthcare providers interested in improving their knowledge base and skill sets in sleep/wake medicine. There are no prerequisites for this educational activity.

Statement of Need

Characterized by their heterogeneity and profound effects on patient function, sleep/wake disorders are prevalent and often inadequately treated, resulting in significant morbidity and mortality. Healthcare-related costs are particularly burdensome, estimated at nearly USD 100 billion per annum. Data from numerous epidemiologic and randomized controlled studies clearly demonstrate that patients with disrupted sleep/wake patterns have significantly impaired function and experience excessive sleepiness, a debilitating symptom with far-reaching consequences. Furthermore, the possibility that comorbidities associated with sleep/wake disorders may not be completely reversible highlights the importance of recognizing these symptoms and consequences. Healthcare providers need to improve their understanding of the morbidity associated with sleep/wake disorders, to communicate the issues to their colleagues and their patients, and to tailor therapies accordingly.

Learner’s Gap

Sleep/wake disorders are underdiagnosed, underrecognized, and undertreated. Evidence-based discussions supported by expert clinical experience provide a scientific and clinical rationale for individualized assessment and treatment of patients with sleep/wake disorders. Emphasizing the biopsychosocial and potentially irreversible consequences of untreated disturbances in sleep/wake consolidation enables clinicians to better assess and manage sleep/wake disorders, and thereby improve patient outcomes.
 

Learning Objectives

At the completion of this initiative, the participants should be better prepared to:
 

  • Discuss the morbidity associated with obstructive sleep apnea, shift work sleep disorder, and other common sleep/wake disorders across biological, psychological, and social domains
  • Recognize, evaluate, and diagnose patients presenting with excessive sleepiness and signs and symptoms associated with obstructive sleep apnea, shift work sleep disorder, and other common sleep/wake disorders
  • Stratify patients by risk and severity of obstructive sleep apnea and other common sleep/wake disorders and develop appropriate referral and long-term management plans
  • Employ nonpharmacologic and pharmacologic treatment modalities to ameliorate underlying causes, signs, and symptoms of common sleep/wake disorders
  • Monitor treatment compliance and therapeutic progress of patients with obstructive sleep apnea and other common sleep/wake disorder–related signs and symptoms

Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Albert Einstein College of Medicine and Montefiore Medical Center, and Asante Communications. Albert Einstein College of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

Albert Einstein College of Medicine designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Conflict of Interest Statement

The Conflict of Interest Disclosure Policy of Albert Einstein College of Medicine requires that faculty participating in any CME activity disclose to the audience any relationship(s) with a pharmaceutical, product, or device company. Any presenter whose disclosed relationships prove to create a conflict of interest with regard to their contribution to the activity will not be permitted to present.

Albert Einstein College of Medicine also requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.

Faculty participating in this activity have reported the following disclosures:

Thomas Roth, PhD
Acorda (Consultant); Actelion (Consultant); Addrenex (Consultant); Arena (Consultant); Aventis (Grant/Research, Consultant); BTG (Consultant); Cephalon (Grant/Research, Consultant, Speakers Bureau); Eisai (Consultant); GlaxoSmithKline (Grant/Research, Consultant); Intec (Consultant); Intra-Cellular (Consultant); McNeil (Consultant); Merck (Consultant); Neurim (Consultant); Neurocrine (Grant/Research, Consultant); Otsuka (Consultant); Pfizer (Grant/Research, Consultant); sanofi-aventis (Grant/Research, Consultant, Speakers Bureau); Schering-Plough (Grant/Research, Consultant); Sepracor (Grant/Research, Consultant); Shire (Consultant); Somaxon (Grant/Research, Consultant); Syrex (Grant/Research, Consultant); Takeda (Grant/Research, Consultant, Speakers Bureau); TransOral (Grant/Research, Consultant); Wyeth (Grant/Research, Consultant); Xenoport (Grant/Research, Consultant)

Michael J. Thorpy, MD Cephalon, Inc.; Jazz Pharmaceuticals
(consultant, speakers bureau)

Andrew G. Israel, MD
sanofi-aventis (Consultant)

Andrew D. Krystal, MD, MS
Actelion (Consultant); Arena (Consultant); Astellas (Grant/Research, Consultant); AstraZeneca (Consultant); Axiom (Consultant); Bristol-Myers Squibb (Consultant); Cephalon (Grant/Research, Consultant); CHDI (Consultant); Eli Lilly (Consultant); Evotec (Consultant); GlaxoSmithKline (Consultant); Jazz (Consultant); Johnson and Johnson (Consultant); King (Consultant); Kingsdown Inc. (Consultant); Merck (Grant/Research, Consultant); Neurocrine (Grant/Research, Consultant); Neurogen (Grant/Research, Consultant); NIH (Consultant); Neuronetics (Grant/Research, Consultant), Novartis (Consultant); Organon (Consultant); Ortho-McNeil-Janssen (Consultant); Pfizer (Grant/Research, Consultant); Research Triangle Institute (Consultant); Respironics (Grant/Research, Consultant); Roche (Consultant); sanofi-aventis (Grant/Research, Consultant), Sepracor (Consultant); Somaxon (Grant/Research, Consultant); Takeda (Grant/Research, Consultant); Transcept (Grant/Research, Consultant)

One staff member at Albert Einstein College of Medicine has reported the following disclosures:

Steven Jay Feld, or a member of his household, owns securities in Bioheart, Inc.; Chelsea Therapeutics, Inc.; and Pharmacopeia, Inc.

Chris Ontiveros, PhD, (senior scientific associate, Asante Communications, LLC) has no conflicts of interest with commercial interests related directly or indirectly to this educational activity.

Method of Participation

There are no fees for participating in and receiving credit for this activity. Participants must read the objectives and enduring material, and answer the multiple-choice posttest. Please complete the evaluation form, which enables you to comment on the quality of the instructional process, the perception of enhanced professional effectiveness and commercial bias, and express your views on future educational needs. A score of at least 70% is required to successfully complete this activity. Credit is available through February 15, 2011.

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Copyright Information

Copyright © 2010 Albert Einstein College of Medicine and Montefiore Medical Center, and Asante Communications. All rights reserved. No part of this syllabus may be used or reproduced in any manner whatsoever without written permission, except in the case of brief quotations embodied in articles or reviews.

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