Long-term Abuse Liability of Zolpidem in Insomniacs

Timothy A. Roehrs, PhD

Director of Research
Sleep Disorders & Research Center
Henry Ford Hospital
Professor
Department of Psychiatry and Behavioral Neuroscience
Wayne State University
School of Medicine
Detroit, Michigan

It is well-eatablished that hypnotics vary in their abuse liability. Because hypnotics may be prescribed for long-term management of impaired sleep, clinicians need to understand patient risk of inappropriate use of these medications over time. A recent study with zolpidem demonstrated no change in abuse liability among insomniacs over a period of 4 months of use.

References

Predictors of Clinical Pain in Fibromyalgia: Examining the Role of Sleep

Anderson RJ, McCrae CS, Staud R, Berry RB, Robinson ME.
Department of Clinical and Health...

Bidirectional interactions between circadian entrainment and cognitive performance

Gritton HJ, Kantorowski A, Sarter M, Lee TM.
Department of Psychology, University of...

Subjective, anatomical, and functional nasal evaluation of patients with obstructive sleep apnea syndrome

de Aguiar Vidigal T, Martinho Haddad FL, Gregório LC, Poyares D, Tufik S, Azeredo...

Sleep disturbances and fatigue: independent predictors of sickness absence? A prospective study among 6538 employees

Bültmann U, Nielsen MB, Madsen IE, Burr H, Rugulies R.
Department of Health Sciences,...

The role of presleep negative emotion in sleep physiology

Vandekerckhove M, Weiss R, Schotte C, Exadaktylos V, Haex B, Verbraecken J, Cluydts R....